Fabrication and Cytocompatibility of the Nanocomposite Chitosan and Phosphorylatd Chitosan

Objective:To synthesize a new bone repair material composed of chitosan and phosphorylated chitosan (CS/PCS) and to evaluate its cytocompatibility in vitro.Methods:Phosphate group was incorporated into chitosan(CS) to form phosphorylated chitosan(PCS).The PCS solution was dropped into the acetic acid solution of CS to get the complex of chitosan and phosphorylated chitosan(CS/PCS).CS/PCS hydrocolloid was co-cultured with rat osteoblasts in vitro...