Role of PI3K/Akt signaling pathway in P12 cells apoptosis induced by β-amyloid peptide

Abstract
AIM: To investigate the role of PI3K/Akt signaling pathway on cell apoptosis induced by β-amyloid peptide in PC12 cells.METHODS: The viability of PC12 cells and the levels of p-AktSer473 and p-GSK-3βSer9 were detected by MTT and Western blotting,respectively.Cell apoptosis was determined by Annexin V-PI staining.RESULTS: Aβ25-35 treatment decreased the viability of PC12 cells in a time-depended manner(P0.05).Annexin V-PI staining demonstrated...
Paper Details
Title
Role of PI3K/Akt signaling pathway in P12 cells apoptosis induced by β-amyloid peptide
Published Date
Jan 1, 2009
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.