Preparation and in vitro-in vivo Correlation Analysis in Rabbits of Total Glycosides Sustained-Release Tablets of Sanqing Jiangtang Decoction
Abstract
Objective: To optimize prescription of total glycosides sustained-release tablets of Sanqing Jiangtang decoction,then investigate its in vitro release profile and pharmacokinetics in rabbits. Method: With hydroxypropyl methyl cellulose(HPMC) as matrix material, sustained-release tablets was prepared by wet granulation tableting technique. With cumulative release rates in 1,4,8,12 h as comprehensive evaluation index,orthogonal test was adopted to...
Paper Details
Title
Preparation and in vitro-in vivo Correlation Analysis in Rabbits of Total Glycosides Sustained-Release Tablets of Sanqing Jiangtang Decoction
Published Date
Jan 1, 2013
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