YY1 Is Required for Germinal Center B Cell Development
Abstract
YY1 has been implicated as a master regulator of germinal center B cell development as YY1 binding sites are frequently present in promoters of germinal center-expressed genes. YY1 is known to be important for other stages of B cell development including the pro-B and pre-B cells stages. To determine if YY1 plays a critical role in germinal center development, we evaluated YY1 expression during B cell development, and used a YY1 conditional...
Paper Details
Title
YY1 Is Required for Germinal Center B Cell Development
Published Date
May 11, 2016
Journal
Volume
11
Issue
5
Pages
e0155311 - e0155311
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