Study on apoptosis-inducing effect for mouse mammary cancer cells transfected with IL-23 gene in vitro and in vivo
Abstract
Objective:To investigate the changes in apoptosis of mouse mammary cancer cells (MA-891) after transfection with IL-23 gene in vitro and in vivo and explore the anti-tumor mechanism of IL-23. Methods: IL-23 gene was transferred into two packing cell lines (ectotrophic ψ2 and amphotrophic PA317) in sequence by a retrovirus vector (LXSN), and the positive cellular clones that can produce retroviruses carrying IL-23 gene were screened by G418. The...
Paper Details
Title
Study on apoptosis-inducing effect for mouse mammary cancer cells transfected with IL-23 gene in vitro and in vivo
Published Date
Jan 1, 2008
Journal
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