Role of NOX2 in mediating doxorubicin-induced senescence in human endothelial progenitor cells
Abstract
Senescence exerts a great impact on both biological and functional properties of circulating endothelial progenitor cells (EPCs), especially in cardiovascular diseases where the physiological process of aging is accelerated upon clinical administration of certain drugs such as doxorubicin. EPC impairment contributes to doxorubicin-induced cardiotoxicity. Doxorubicin accelerates EPC aging, although mechanisms underlying this phenomenon remain to...
Paper Details
Title
Role of NOX2 in mediating doxorubicin-induced senescence in human endothelial progenitor cells
Published Date
Oct 1, 2016
Volume
159
Pages
37 - 43
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