In vitro and in vivo evaluation of pioglitazone hydrochloride/metformin hydrochloride sustained-release tablets
Abstract
Objective:To prepare pioglitazone hydrochloride(PH)/metformin hydrochloride(MH) sustained-release tablets,and evaluate their release behaviors in vitro and in vivo.Methods:The MH sustained-release part was prepared by hydrophilic matrix combined with sustained release film coating technology.The HPMC K100M and EudragitNE 30D were used as hydrophilic matrix and film coating.The PH immediate-release part was prepared by coating technology.The...
Paper Details
Title
In vitro and in vivo evaluation of pioglitazone hydrochloride/metformin hydrochloride sustained-release tablets
Published Date
Jan 1, 2014
Journal
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