Human iPSC-derived endothelial cell sprouting assay in synthetic hydrogel arrays
Abstract
Activation of vascular endothelial cells (ECs) by growth factors initiates a cascade of events during angiogenesis in vivo consisting of EC tip cell selection, sprout formation, EC stalk cell proliferation, and ultimately vascular stabilization by support cells. Although EC functional assays can recapitulate one or more aspects of angiogenesis in vitro, they are often limited by undefined substrates and lack of dependence on key angiogenic...
Paper Details
Title
Human iPSC-derived endothelial cell sprouting assay in synthetic hydrogel arrays
Published Date
Jul 1, 2016
Journal
Volume
39
Pages
12 - 24
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Notes
History