Phenotypic Transition as a Survival Strategy of Glioma
Abstract
Malignant glioma is characterized by rapid proliferation, invasion into surrounding central nervous system tissues, and aberrant vascularization. There is increasing evidence that shows gliomas are more complex than previously thought, as each tumor comprises considerable intratumoral heterogeneity with mixtures of genetically and phenotypically distinct subclones. Heterogeneity within and across tumors is recognized as a critical factor that...
Paper Details
Title
Phenotypic Transition as a Survival Strategy of Glioma
Published Date
Jan 1, 2016
Journal
Volume
56
Issue
7
Pages
387 - 395
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Notes
History