Selective oxidation of betulin for betulinic acid preparation

Abstract
A selective oxidation for synthesis of betulinic acid from betulin has been developed.This system was applied to selectively oxide of the primary alcohol function of betulin without affecting the secondary hydroxyl group.The reaction can be carried out in butyl acetate at 25 ℃ for 1 h,using 1,3-dibromo-5,5-dimethylhydantoin(DBDMH) in the presence of catalyst TEMPO,in which the yield of betulinic acid is...
Paper Details
Title
Selective oxidation of betulin for betulinic acid preparation
Published Date
Jan 1, 2009
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