Tumor Microenvironment Affecting Biological Behaviour of Malignant Ovarian Neoplasms: an Update

The tumor microenvironment is a tumor cell,stromal cells,cytokines,immune cells such as tumor constitute the environment of local pathology,which is tissue hypoxia,acidosis,interstitial high pressure and so on.In tumor microenvironment in a large number of growth factors,proteolytic enzymes and the immune inflammatory response which interact on the tumor cell surface,play an important impact on cell proliferation,metastasis,differentiation.Early...