Serum LDL-C increased by PCSK9 in LPS-treated mice model

Abstract
Objective:To study the effect of PCSK9 on the LDL-C metabolism in response to infection and inflammation.Methods:C57B / 6J male mice were injected with low dose liposaccharide(LPS) to mimic acute phase responce.Plasma lipids levels were detected.Serum amyloid A levels in peripheral circulation and purified fast protein liquid chromatography(FPLC) fractions have been assayed by ELISA.Real time PCR has been used to measure PCSK9,LDLR,HMGR and...
Paper Details
Title
Serum LDL-C increased by PCSK9 in LPS-treated mice model
Published Date
Jan 1, 2011
Journal
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