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doi.org/10.1038/nm.4096

A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus

..., Daniel R. Weinberger
17
Nature Medicine82.90
Volume: 22, Issue: 6, Pages: 649 - 656
Published: May 9, 2016
Abstract
eQTL analysis of human brain RNA-seq data targeted to genes within the 10q24.32 schizophrenia-associated locus reveals that the risk SNP in this region is selectively associated with expression of BORCS7 and a human-specific isoform of AS3MT across multiple independent samples. Expression of only the associated AS3MT isoform is higher in tissue from humans with schizophrenia than in healthy...
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Paper Details
Title
A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus
DOI
doi.org/10.1038/nm.4096
Published Date
May 9, 2016
Journal
Nature Medicine
Volume
22
Issue
6
Pages
649 - 656
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