Degradable UV-crosslinked hydrogel for the controlled release of triclosan with reduced cytotoxicity

In order to realize the controlled release and limited toxicity of triclosan (TC), a degradable UV-crosslinked hydrogel was prepared. For this purpose, the acryloyl chloride-modified polyactide-poly(ethylene glycol)-polylactide block copolymer was firstly synthesized and then mixed with photoinitiator to form the hydrogel rapidly under a low-intensity UV light. The properties of hydrogel, such as hydrogel strength, swelling and degradation, had...