Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells

Volume: 31, Issue: sup1, Pages: 119 - 125
Published: May 3, 2016
Abstract
Context: Proton Pump Inhibitors (PPIs) reduce tumor acidity and therefore resistance of tumors to drugs. Carbonic Anhydrase IX (CA IX) inhibitors have proven to be effective against tumors, while tumor acidity might impair their full effectiveness.Objective: To analyze the effect of PPI/CA IX inhibitors combined treatment against human melanoma cells.Methods: The combination of Lansoprazole (LAN) and CA IX inhibitors (FC9-399A and S4) has been...
Paper Details
Title
Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells
Published Date
May 3, 2016
Volume
31
Issue
sup1
Pages
119 - 125
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