Diagnosis of Giant Cell Arteritis in an Asymptomatic Patient

Published on Nov 1, 2015in Arthritis & Rheumatism9.586
· DOI :10.1002/ART.39517
Drew Pratt10
Estimated H-index: 10
#1Ingo Einspieler (TUM: Technische Universität München)H-Index: 9
#2Klaus Thürmel (TUM: Technische Universität München)H-Index: 10
Last. Markus EsslerH-Index: 30
view all 8 authors...
Purpose The aim of this study was to evaluate the feasibility of hybrid [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET)/MRI in patients with large vessel vasculitis (LVV) by comparing visual and quantitative parameters to that of PET/CT. Furthermore, the value of PET/MRI in disease activity and extent of LVV was assessed.
#1Michael Soussan (Sorbonne)H-Index: 28
#2Patrick NicolasH-Index: 20
Last. Arsène MekinianH-Index: 43
view all 7 authors...
We aimed to clarify the role of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in the management of large-vessel vasculitis (LVV), focusing on 3 issues which are as follows: describe and determine the different FDG-PET criteria for the diagnosis of vascular inflammation, the performance of FDG-PET for the diagnosis of large-vessel inflammation in giant cell arteritis (GCA) patients, and the performance of FDG-PET to evaluate the disease inflammatory activity in Takayasu arteritis ...
#1Peter C. Grayson (BU: Boston University)H-Index: 27
#2Kathleen Maksimowicz-McKinnon (Cleveland Clinic)H-Index: 22
Last. Gary S. Hoffman (Cleveland Clinic)H-Index: 77
view all 14 authors...
Objectives To compare patterns of arteriographic lesions of the aorta and primary branches in patients with Takayasu9s arteritis (TAK) and giant cell arteritis (GCA). Methods Patients were selected from two North American cohorts of TAK and GCA. The frequency of arteriographic lesions was calculated for 15 large arteries. Cluster analysis was used to derive patterns of arterial disease in TAK versus GCA and in patients categorised by age at disease onset. Using latent class analysis, computer de...
Cited By5
Objective To compare the presence of head, neck and upper extremity symptoms in patients with Takayasu’s (TAK) and giant cell arteritis (GCA) and their association with vascular inflammation assessed by 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) or arterial damage assessed by magnetic resonance angiography (MRA). Methods Patients with TAK and GCA underwent clinical and imaging assessments within 24 hours, blinded to each other. Vascular inflammation was defined as arterial FDG...
#1Matthieu Pelletier-Galarneau (UdeM: Université de Montréal)H-Index: 11
#2Terrence D. Ruddy (U of O: University of Ottawa)H-Index: 47
Purpose of Review This review aims to discuss the use of fluorodeoxyglucose (FDG) positron emission tomography (PET/CT) for diagnosis and management of patients with large-vessel vasculitis (LVV).
#1Kaitlin A. Quinn (NIH: National Institutes of Health)H-Index: 9
#2Peter C. Grayson (NIH: National Institutes of Health)H-Index: 27
Purpose of the review The two main forms of large-vessel vasculitis (LVV) are giant cell arteritis (GCA) and Takayasu’s arteritis (TAK). Vascular imaging can characterize disease activity and disease extent in LVV. This review critically analyzes the clinical utility of vascular imaging in LVV and highlights how imaging may be incorporated into the management and study of these conditions.
#1Kaitlin A. QuinnH-Index: 9
#2Mark A. Ahlman (NIH: National Institutes of Health)H-Index: 21
Last. Peter C. Grayson (NIH: National Institutes of Health)H-Index: 27
view all 10 authors...
Objectives To assess agreement between interpretation of magnetic resonance angiography (MRA) and 18 F-fluorodeoxyglucose positron emission tomography (PET) for disease extent and disease activity in large-vessel vasculitis (LVV) and determine associations between imaging and clinical assessments. Methods Patients with giant cell arteritis (GCA), Takayasu’s arteritis (TAK) and comparators were recruited into a prospective, observational cohort. Imaging and clinical assessments were performed con...
#1Peter C. GraysonH-Index: 27
#2Sara AlehashemiH-Index: 10
Last. Mark A. AhlmanH-Index: 21
view all 11 authors...
Objectives To assess the clinical value of 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) in a prospective cohort of patients with large-vessel vasculitis (LVV) and disease comparators. Methods Patients with Takayasu's arteritis (TAK) and giant cell arteritis (GCA) were studied, along with a comparator group consisting of patients with hyperlipidemia, diseases that mimic LVV, and healthy controls. Participants underwent clinical evaluation and FDG-PET imaging, and patients with L...
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