Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro
Abstract
Bv8/prokineticin 2 (PK2) is a member of a bioactive family of peptides that regulate multiple functions in the CNS including hyperalgesia, neurogenesis, neuronal survival and inflammation. Recent studies have associated PK2 and prokineticin receptors (PKR) with human diseases, but because their role in neuropathology is still debated we examined whether prokineticins exert a protective or deleterious role in models of cerebral ischemia and...
Paper Details
Title
Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro
Published Date
Sep 1, 2016
Journal
Volume
108
Pages
39 - 48
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