Chapter 10:Thiirane Class of Gelatinase Inhibitors as a Privileged Template that Crosses the Blood–Brain Barrier

Pages: 262 - 286
Published: Nov 20, 2015
Abstract
The gelatinases (matrix metalloproteinase (MMP)-2 and MMP-9) play important roles in the pathophysiology of several diseases, including cancer metastases, neurological diseases, and chronic wounds. MMPs also mediate beneficial repair and recovery functions. Thus, the use of selective MMP inhibitors is required to avoid side effects. The prototype gelatinase inhibitor SB-3CT displays potency and selectivity towards the gelatinases. SB-3CT...
Paper Details
Title
Chapter 10:Thiirane Class of Gelatinase Inhibitors as a Privileged Template that Crosses the Blood–Brain Barrier
Published Date
Nov 20, 2015
Pages
262 - 286
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.