VEGF released from a fibrin biomatrix increases VEGFR-2 expression and improves early outcome after ischaemia-reperfusion injury

Volume: 11, Issue: 7, Pages: 2153 - 2163
Published: Jan 17, 2016
Abstract
Skeletal ischaemia–reperfusion (I–R) injury may influence patient outcome after severe vascular trauma or clamping of major vessels. The aim of this study was to observe whether locally applied vascular endothelial growth factor (VEGF) in fibrin could induce the expression of VEGF-receptor-2 (VEGFR-2) and improve the outcome after I–R injury. Transgenic mice expressing VEGFR-2 promoter-controlled luciferase were used for the assessment of...
Paper Details
Title
VEGF released from a fibrin biomatrix increases VEGFR-2 expression and improves early outcome after ischaemia-reperfusion injury
Published Date
Jan 17, 2016
Volume
11
Issue
7
Pages
2153 - 2163
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