Cellular localization of guanylin and uroguanylin mRNAs in human and rat duodenal and colonic mucosa
Abstract
Guanylin (GUCA2A/Guca2a/GN) and uroguanylin (GUCA2B/Guca2b/UGN) are expressed in the gastrointestinal tract and have been implicated in ion and fluid homeostasis, satiety, abdominal pain, growth and intestinal barrier integrity. Their cellular sources are debated and include goblet cells, entero-/colonocytes, enteroendocrine (EE) cells and tuft cells. We therefore investigated the cellular sources of GN and UGN mRNAs in human and rat duodenal...
Paper Details
Title
Cellular localization of guanylin and uroguanylin mRNAs in human and rat duodenal and colonic mucosa
Published Date
Apr 5, 2016
Journal
Volume
365
Issue
2
Pages
331 - 341
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