Abstract A134: MiR-875-5p impairs prostate cancer metastasis by remodeling tumor secretome and enhances tumor radiation response via EGFR suppression

Published: Dec 1, 2015
Abstract
Acquisition of mesenchymal features by carcinoma cells through the epithelial-mesenchymal transition (EMT) is responsible for the initiation and sustainment of the metastatic cascade, as well as the establishment of a chemo- and radio-resistant phenotype. In prostate cancer (PCa), metastatic disease remains incurable despite the approval of several new drugs for clinical use in recent years. In addition, emergence of resistance to radiotherapy,...
Paper Details
Title
Abstract A134: MiR-875-5p impairs prostate cancer metastasis by remodeling tumor secretome and enhances tumor radiation response via EGFR suppression
Published Date
Dec 1, 2015
Journal
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