Regulatory Role of IL-1R8 in Immunity and Disease
Abstract
Interleukin-1 receptor family members (ILRs) and toll-like receptors (TLRs) are characterized by the presence of a conserved intracellular domain and the toll-IL-1resistance (TIR) domain and are key players in immunity and inflammation. ILR and TLR signaling is tightly regulated at different levels. All cell types of the innate immune system express ILRs and TLRs. In addition, IL-1 family members are emerging as key players in the...
Paper Details
Title
Regulatory Role of IL-1R8 in Immunity and Disease
Published Date
Apr 20, 2016
Journal
Volume
7
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