Perioperative Normothermia to Reduce the Incidence of Surgical-Wound Infection and Shorten Hospitalization
Abstract
Mild perioperative hypothermia, which is common during major surgery, may promote surgical-wound infection by triggering thermoregulatory vasoconstriction, which decreases subcutaneous oxygen tension. Reduced levels of oxygen in tissue impair oxidative killing by neutrophils and decrease the strength of the healing wound by reducing the deposition of collagen. Hypothermia also directly impairs immune function. We tested the hypothesis that...
Paper Details
Title
Perioperative Normothermia to Reduce the Incidence of Surgical-Wound Infection and Shorten Hospitalization
Published Date
May 9, 1996
Volume
334
Issue
19
Pages
1209 - 1216
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