Comparison of three generic vancomycin products using liquid chromatography-mass spectrometry and an online tool.
Volume: 71, Issue: 12, Pages: 1029 - 1038
Published: Jun 15, 2014
Abstract
Purpose Three different generic vancomycin products were compared using liquid chromatography–mass spectrometry (LC-MS) and open-access metabolomic tools.
Methods Single-lot samples of vancomycin hydrochloride from three different manufacturers (Hospira, APP Pharmaceuticals, and Pfizer) were reconstituted and injected into a high-resolution LC-MS system. The mass spectral fingerprints were compared for similarity of nonvancomycin B components...
Paper Details
Title
Comparison of three generic vancomycin products using liquid chromatography-mass spectrometry and an online tool.
Published Date
Jun 15, 2014
Volume
71
Issue
12
Pages
1029 - 1038
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