Amentoflavone Protects against Hydroxyl Radical-induced DNA Damage via Antioxidant Mechanism

Objective: Oxidative DNA damage is involved in mutation, cell death, carcinogenesis, and aging. Since biflavonoid amentoflavone exhibited beneficial effects on DNA, we therefore investigated its protection against •OH-induced DNA oxidative damage then discussed the mechanism. It will enhance the understanding of interaction between biflavonoid vs DNA mediated by free radicals. Methods: The protective effect of amentoflavone against •OH-induced...