Tissue-Specific Regulation of Genes by Estrogen Receptors

Volume: 30, Issue: 01, Pages: 14 - 22
Published: Jan 1, 2012
Abstract
Estrogens are frequently used in reproductive medicine. The Women’s Health Initiative trial found that the risks of menopausal hormone therapy (MHT) exceed the benefits. The estrogens in MHT, however, were introduced prior to our understanding of the mechanism of action of estrogens. Estrogen signaling is highly complex, involving various DNA regulatory elements to which estrogen receptors bind. Numerous transcription factors and co-regulatory...
Paper Details
Title
Tissue-Specific Regulation of Genes by Estrogen Receptors
Published Date
Jan 1, 2012
Volume
30
Issue
01
Pages
14 - 22
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