Novel inhibitors of poly(ADP-ribose) synthetase
Abstract
In a search for new inhibitors of the nuclear enzyme poly(ADP-ribose) synthetase, it was found that various benzamides substituted in the 3-position were the most inhibitory compounds found to date. Two of the benzamides, 3-aminobenzamide and 3-methoxybenzamide, were found to be competitive inhibitors, with Ki values or less than 2...
Paper Details
Title
Novel inhibitors of poly(ADP-ribose) synthetase
Published Date
Mar 1, 1980
Journal
Volume
185
Issue
3
Pages
775 - 777
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Notes
History