Single-Molecule Analysis Enables Free Solution Hydrodynamic Separation Using Yoctomole Levels of DNA
Volume: 133, Issue: 18, Pages: 6898 - 6901
Published: Apr 19, 2011
Abstract
Single-molecule free solution hydrodynamic separation (SML-FSHS) cohesively integrates cylindrical illumination confocal spectroscopy with free solution hydrodynamic separation. This technique enables single-molecule analysis of size separated DNA with 100% mass detection efficiency, high sizing resolution and wide dynamic range, surpassing the performance of single molecule capillary electrophoresis. Furthermore, SML-FSHS required only a bare...
Paper Details
Title
Single-Molecule Analysis Enables Free Solution Hydrodynamic Separation Using Yoctomole Levels of DNA
Published Date
Apr 19, 2011
Volume
133
Issue
18
Pages
6898 - 6901
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