Caffeic acid protects mice from memory deficits induced by focal cerebral ischemia
Abstract
Brain ischemia pathophysiology involves a complex cascade of events such as inflammation and oxidative stress that lead to neuronal loss and cognitive deficits. Caffeic acid (CA) is a natural phenolic compound with antioxidant and anti-inflammatory properties. To evaluate the neuroprotective efficacy of this compound in mice subjected to a permanent middle cerebral artery occlusion, animals were pretreated and post-treated with CA, 2, 20, and 60...
Paper Details
Title
Caffeic acid protects mice from memory deficits induced by focal cerebral ischemia
Published Date
Oct 1, 2014
Journal
Volume
25
Issue
7
Pages
637 - 647
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Notes
History