Sustained Neuroprotection From a Single Intravitreal Injection of PGJ2in a Nonhuman Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy
Volume: 55, Issue: 11, Pages: 7047 - 7047
Published: Nov 5, 2014
Abstract
Purpose.: Prostaglandin J2 (PGJ2) is neuroprotective in a murine model of nonarteritic anterior ischemic optic neuropathy (NAION). After assessing for potential toxicity, we evaluated the efficacy of a single intravitreal (IVT) injection of PGJ2 in a nonhuman primate model of NAION (pNAION). Methods.: We assessed PGJ2 toxicity by administering it as a single high-dose intravenous (IV) injection, consecutive daily high-dose IV injections, or a...
Paper Details
Title
Sustained Neuroprotection From a Single Intravitreal Injection of PGJ2in a Nonhuman Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy
Published Date
Nov 5, 2014
Volume
55
Issue
11
Pages
7047 - 7047
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