Safety and efficacy of cell-based therapy on critical limb ischemia: A meta-analysis

Background aims Critical limb ischemia (CLI) is a major health problem worldwide, affecting approximately 500–1000 people per million per annum. Cell-based therapy has given new hope for the treatment of limb ischemia. This study assessed the safety and efficacy of cellular therapy CLI treatment. Methods We searched the PubMed, Embase and Cochrane databases through October 20, 2015, and selected the controlled trials with cell-based therapy for...