Relationship between Serum Vitamin-A Concentration and Hepatic Stellate Cells in Cows with Fatty-liver Disease

Vitamin A (VA) is stored mainly in lipid droplets in hepatic stellate cells (HSCs) of the liver. Apparently, when the level of serum VA drops below the basic-requirement level, lipid droplets in an HSC either decrease in number or disappear altogether. Fatty-liver disease (fat-cow syndrome), which is common in periparturient cattle and makes the animals highly susceptible to ketosis, is a major cause of significant economic loss. In the past,...