Histopathologic and Immunohistochemical Features in Human Skin after Exposure to Nitrogen and Sulfur Mustard
Abstract
N-methyl-2,2'-dichlorodiethylamine (HN2)is a topical chemotherapeutic agent used as therapy for cutaneous T-cell lymphomas (CTCL). Di(2-chloroethyl)sulfide (SM), and less often HN2, have been used as chemical weapons, with the skin being a principle target. The mechanisms by which these chemicals produce their therapeutic and toxic effects in skin, however, are not clearly defined. We exposed human skin explants to two doses of HN2 and SM. At 18...
Paper Details
Title
Histopathologic and Immunohistochemical Features in Human Skin after Exposure to Nitrogen and Sulfur Mustard
Published Date
Feb 1, 1998
Volume
20
Issue
1
Pages
22 - 28
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