Central Nervous System Multiparameter Optimization Desirability: Application in Drug Discovery

Volume: 7, Issue: 6, Pages: 767 - 775
Published: Apr 4, 2016
Abstract
Significant progress has been made in prospectively designing molecules using the central nervous system multiparameter optimization (CNS MPO) desirability tool, as evidenced by the analysis reported herein of a second wave of drug candidates that originated after the development and implementation of this tool. This simple-to-use design algorithm has expanded design space for CNS candidates and has further demonstrated the advantages of...
Paper Details
Title
Central Nervous System Multiparameter Optimization Desirability: Application in Drug Discovery
Published Date
Apr 4, 2016
Volume
7
Issue
6
Pages
767 - 775
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