Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs.
Abstract
Cyclins and cyclin-dependent protein kinases (CDKs) are important regulatory components that are required for cell cycle progression. The levels of the cell cycle CDKs are generally constant and their activities are controlled by cyclins, proteins whose levels oscillate during each cell cycle. Additional CDK family members were subsequently discovered that play significant roles in a wide range of activities including the control of gene...
Paper Details
Title
Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs.
Published Date
May 1, 2016
Journal
Volume
107
Issue
107
Pages
249 - 275
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Notes
History