Type 2 innate lymphoid cells: at the cross-roads in allergic asthma
Abstract
Allergic asthma is a chronic inflammatory disease of the lower airways that affects millions of people worldwide. Allergic asthma is a T helper 2 cell (Th2)-mediated disease, in which Th2 cytokines interleukin (IL)-4, IL-5, and IL-13 are closely associated with the symptoms. IL-4 is needed by B cells to switch toward an IgE response, IL-5 recruits and activates eosinophils while IL-13 increases mucus production. The identification of type 2...
Paper Details
Title
Type 2 innate lymphoid cells: at the cross-roads in allergic asthma
Published Date
Mar 10, 2016
Journal
Volume
38
Issue
4
Pages
483 - 496
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