The possible role of intravenous lipid emulsion in the treatment of chemical warfare agent poisoning
Abstract
Organophosphates (OPs) are cholinesterase inhibitors that lead to a characteristic toxidrome of hypersecretion, miosis, dyspnea, respiratory insufficiency, convulsions and, without proper and early antidotal treatment, death. Most of these compounds are highly lipophilic. Sulfur mustard is a toxic lipophilic alkylating agent, exerting its damage through alkylation of cellular macromolecules (e.g., DNA, proteins) and intense activation of...
Paper Details
Title
The possible role of intravenous lipid emulsion in the treatment of chemical warfare agent poisoning
Published Date
Jan 1, 2016
Journal
Volume
3
Pages
202 - 210
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Notes
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