Purinergic regulation of the immune system

Volume: 16, Issue: 3, Pages: 177 - 192
Published: Mar 1, 2016
Abstract
Cellular stress or apoptosis triggers the release of ATP, ADP and other nucleotides into the extracellular space. Extracellular nucleotides function as autocrine and paracrine signalling molecules by activating cell-surface P2 purinergic receptors that elicit pro-inflammatory immune responses. Over time, extracellular nucleotides are metabolized to adenosine, leading to reduced P2 signalling and increased signalling through anti-inflammatory...
Paper Details
Title
Purinergic regulation of the immune system
Published Date
Mar 1, 2016
Volume
16
Issue
3
Pages
177 - 192
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.