Type VI secretion system sheaths as nanoparticles for antigen display

Volume: 113, Issue: 11, Pages: 3042 - 3047
Published: Feb 29, 2016
Abstract
Significance Critical aspects that limit use of nanoparticles as vaccine delivery systems include the technical difficulty of preparing particles under conditions that allow controlled protein loading and folding. Biologic nanoparticles offer advantages over chemically derived particles that require harsh organic solvents for preparation. Here, we demonstrate that the multimeric sheath structure of the bacterial type 6 secretion system (T6SS)...
Paper Details
Title
Type VI secretion system sheaths as nanoparticles for antigen display
Published Date
Feb 29, 2016
Volume
113
Issue
11
Pages
3042 - 3047
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