Wasted research when systematic reviews fail to provide a complete and up-to-date evidence synthesis: the example of lung cancer

Multiple treatments are frequently available for a given condition, and clinicians and patients need a comprehensive, up-to-date synthesis of evidence for all competing treatments. We aimed to quantify the waste of research related to the failure of systematic reviews to provide a complete and up-to-date evidence synthesis over time.We performed a series of systematic overviews and networks of randomized trials assessing the gap between evidence...