Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma
Abstract
Progression of cancer is often associated with interactions between cancer cells and extracellular matrix (ECM) surrounding them. Increasing evidence has suggested that accumulation of hyaluronan (HA), a major component of ECM, provides a favorable microenvironment for cancer progression. Pancreatic ductal adenocarcinoma (PDAC) is characterized typically by a dense desmoplastic stroma with a large amount of HA, making this molecule as an...
Paper Details
Title
Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma
Published Date
Mar 1, 2016
Journal
Volume
6
Issue
2
Pages
101 - 105
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