Dynamics of epigenetic regulation at the single-cell level
Abstract
Quantitative analysis of epigenetic memory To explore quantitative and dynamic properties of transcriptional regulation by epigenetic modifications, Bintu et al. monitored a transcriptional reporter gene carried on a human artificial chromosome in Chinese hamster ovary cells (see the Perspective by Keung and Khalil). They measured effects of DNA methylation and histone modifications by methylation or deacetylation in single cells using...
Paper Details
Title
Dynamics of epigenetic regulation at the single-cell level
Published Date
Feb 12, 2016
Journal
Volume
351
Issue
6274
Pages
720 - 724
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Notes
History