A non-invasive urine-based research test for the detection of prostate cancer using DNA methylation

AACR Annual Meeting-- Apr 14-18, 2007; Los Angeles, CA 3502 Introduction : The best outcome for patients with prostate cancer (PCa) is seen for those treated at an early stage of the disease. A digital rectal examination (DRE) and the measurement of serum prostate specific antigen (PSA) levels are the current standards for PCa early detection. However, serum PSA testing lacks both sensitivity and specificity, and core biopsies frequently fail...