The Relationship between Intolerance of Uncertainty and Anxiety in Men on Active Surveillance for Prostate Cancer

Published on Jun 1, 2016in The Journal of Urology5.925
· DOI :10.1016/J.JURO.2016.01.108
Hung-Jui Tan20
Estimated H-index: 20
(UCLA: University of California, Los Angeles),
Leonard S. Marks58
Estimated H-index: 58
(UCLA: University of California, Los Angeles)
+ 6 AuthorsAnnette L. Stanton68
Estimated H-index: 68
(UCLA: University of California, Los Angeles)
Purpose: Anxiety may serve as a major barrier to participation in active surveillance. Intolerance of uncertainty, that is the tendency to perceive the potential for negative events as threatening, has been linked to cancer related worry. Accordingly we explored prospectively the relationship of intolerance of uncertainty with anxiety along with other clinical factors among men treated with active surveillance for prostate cancer.Materials and Methods: A total of 119 men with D’Amico low risk prostate cancer participating in active surveillance completed the HADS (Hospital Anxiety and Depression Scale), MAX-PC (Memorial Anxiety Scale for Prostate Cancer), IUS (Intolerance of Uncertainty Scale) and I-PSS (International Prostate Symptom Score) surveys from 2011 to 2014. We evaluated the relationship between anxiety and IUS score after adjusting for patient characteristics, cancer information and I-PSS using bivariable and multivariable analyses.Results: Of the men 18 (15.1%) and 17 (14.3%) reported clinical...
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