Anti-parietal cell antibodies – diagnostic significance
Abstract
Anti-parietal cell antibodies (APCA) are an advantageous tool for screening for autoimmune atrophic gastritis (AAG) and pernicious anemia (PA). The target for APCA is the H+/K+ ATP-ase. It has been demonstrated, that APCA target both, the alpha, and beta subunits of the proton pump, although the major antigen is the alpha subunit. Circulating serum APCA can be detected by means of immunofluorescence, enzyme-linked immunosorbent assay - currently...
Paper Details
Title
Anti-parietal cell antibodies – diagnostic significance
Published Date
Sep 1, 2016
Journal
Volume
61
Issue
2
Pages
175 - 179
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