Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10
Abstract
Peritoneal fibrosis (PF), a serious pathophysiology of peritoneal dialysis (PD), is implicated in various types of chronic inflammation. In the present study, we examined the benefits of interleukin (IL)-10, which exerts anti-inflammatory effects, in an experimental rat model of methylglyoxal (MGO)-induced PF. We injected an adeno-associated virus (AAV) vector encoding rat IL-10 or enhanced green fluorescent protein (GFP) into male...
Paper Details
Title
Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10
Published Date
Dec 1, 2015
Journal
Volume
95
Issue
12
Pages
1353 - 1362
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