Nrf2 in health and disease: current and future clinical implications

Volume: 129, Issue: 12, Pages: 989 - 999
Published: Dec 1, 2015
Abstract
The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) is a major regulator of oxidative stress defence in the human body. As Nrf2 regulates the expression of a large battery of cytoprotective genes, it plays a crucial role in the prevention of degenerative disease in multiple organs. Thus it has been the focus of research as a pharmacological target that could be used for prevention and treatment of chronic diseases such as...
Paper Details
Title
Nrf2 in health and disease: current and future clinical implications
Published Date
Dec 1, 2015
Volume
129
Issue
12
Pages
989 - 999
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