Lgr5 expression is a valuable prognostic factor for colorectal cancer: evidence from a meta-analysis

Lgr5 has recently been identified as a reliable biomarker of cancer stem cells (CSCs) in colorectal cancer (CRC); however, its prognostic value is still controversial. We searched PubMed, Web of Science, and Wanfang databases with identical strategies to retrieve articles. We evaluated the impact of Lgr5 expression on survival of CRC patients through meta-analysis. A total of 12 studies comprising 2600 patients revealed that Lgr5 overexpression...