Simple downstream process based on detergent treatment improves yield and in vivo transduction efficacy of adeno-associated virus vectors

Volume: 2, Pages: 15024 - 15024
Published: Jan 1, 2015
Abstract
Recombinant adeno-associated viruses (rAAV) are promising candidates for gene therapy approaches. The last two decades were particularly fruitful in terms of processes applied in the production and purification of this type of gene transfer vectors. This rapid technological evolution led to better yields and higher levels of vector purity. Recently, some reports showed that rAAV produced by transient tri-transfection method in adherent human...
Paper Details
Title
Simple downstream process based on detergent treatment improves yield and in vivo transduction efficacy of adeno-associated virus vectors
Published Date
Jan 1, 2015
Volume
2
Pages
15024 - 15024
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