Protective effects of icariin on cisplatin-induced acute renal injury in mice.
Abstract
Cisplatin chemotherapy often causes acute kidney injury in cancer patients. Icariin is a bioactive flavonoid, which has renal protection and anti-inflammation effects. This study investigated the mechanism underlying the attenuation of cisplatin-induced renal injury by icariin. BALB/c mice were treated with cisplatin (15 mg/kg) with or without treatment with icariin (30 or 60 mg/kg for 5 days). Renal function, histological changes, degree of...
Paper Details
Title
Protective effects of icariin on cisplatin-induced acute renal injury in mice.
Published Date
Jan 1, 2015
Journal
Volume
7
Issue
10
Pages
2105 - 14
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Notes
History